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Mildronate CAS 76144-81-5 Cardioprotective drugs

Mildronate CAS 76144-81-5

Port: Shenzhen, China
Production Capacity: 100kg/Month
Payment Terms: T/T, D/P, Western Union, Paypal
Powder: Yes
Customized: Customized
Certification: GMP, HSE, ISO 9001, USP, BP
Suitable for: Adult
State: Solid
Purity: >99%

 

 


Product Name Mildronate
CAS 76144-81-5
Appearance White crystalline powder
MF C6H14N2O2
MW 146.19
Purity 99%

Mildronate is a structural analog of carnitine that competes in the inhibition of butyrate betaine hydroxylase, thereby inhibiting the biosynthesis of carnitine, which directly inhibits the transport of carnitine-dependent fatty acids in mitochondria. Inhibition of carnitine biosynthesis can reduce the concentration of intracellular free carnitine and prevent isoproterenol-induced acyl carnitine accumulation. Therefore, the drug has a significant protective effect on the myocardium, resulting in this protective effect at the same time on the hemodynamic parameters had no significant effect, cardiac blood supply and cardiac oxygen consumption was no significant change.、