- 27
- Oct
Mildronate CAS 76144-81-5 Cardioprotective drugs
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Mildronate CAS 76144-81-5Port: Shenzhen, China
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Product Name | Mildronate |
CAS | 76144-81-5 |
Appearance | White crystalline powder |
MF | C6H14N2O2 |
MW | 146.19 |
Purity | 99% |
Mildronate is a structural analog of carnitine that competes in the inhibition of butyrate betaine hydroxylase, thereby inhibiting the biosynthesis of carnitine, which directly inhibits the transport of carnitine-dependent fatty acids in mitochondria. Inhibition of carnitine biosynthesis can reduce the concentration of intracellular free carnitine and prevent isoproterenol-induced acyl carnitine accumulation. Therefore, the drug has a significant protective effect on the myocardium, resulting in this protective effect at the same time on the hemodynamic parameters had no significant effect, cardiac blood supply and cardiac oxygen consumption was no significant change.、