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Rivaroxaban CAS 366789-02-8

Rivaroxaban CAS 366789-02-8

Port: Shenzhen, China
Transport Package: Aluminum Foil Bag Inside, Then Waterproof Bag
Payment Terms: T/T, D/P, Western Union, Paypal
Powder: Yes
Certification: GMP, HSE, ISO 9001, USP, BP
State: Powder
Purity: >99%
Product Name: Rivaroxaban
CAS: 366789-02-8

 


Prodcut name Rivaroxaban
Standard packing material Aluminum foil bag inside, then waterproof bag or carton
Appearance White  white
Purity 99%
Storage Preserve in tight,light-resistant containers in a cool place

Venous thromboembolism continues to be a major health concern despite conventional anticoagulation therapies. Rivaroxaban is a recent market introduction that directly inhibits FXa with high potency (Ki=0.4 nM; IC50=0.7 nM) and selectivity>10,000-fold over other related serine (thrombin, trypsin, plasmin, FVIIa, FIXa, FXIa, urokinase, and activated protein C). From the X-ray crystal structure, the central oxazolidinone moiety anchors the drug through two hydrogen bonds to Gly219 and directs the morpholinone group into the S4 pocket and the chlorothiophene portion into the S1 pocket. These key components may be coupled together synthetically by a couple of routes. Condensation of 3-morpholinone with 4-fluoronitrobenzene followed by catalytic hydrogenation provides N-(p-aminophenyl)morpholinone for subsequent reaction with (S)-2-(phthalimidomethyl)oxirane. With establishment of the aminoalcohol adduct, cyclization with 1,1′-carbonyldiimidazole generates the central oxazolidinone. Depr

Uses:

Rivaroxaban is recommended as an option for treating pulmonary embolism and preventing recurrent deep vein thrombosis and pulmonary embolism in adults.
1. Rivaroxaban (Xarelto, Bayer) is indicated for the ‘treatment of deep vein thrombosis and pulmonary embolism, and prevention of recurrent deep vein thrombosis and pulmonary embolism in adults’. For the initial treatment of acute pulmonary embolism, the recommended dosage of rivaroxaban is 15 mg twice daily for the first 21 days followed by 20 mg once daily for continued treatment and prevention of recurrent venous thromboembolism.
2. Non-Valvular Atrial Fibrillation (NVAF)* to prevent stroke & systemic embolism.
3. Acute VTE treatment & prevention of recurrent VTE [for deep vein thrombosis (DVT) and pulmonary embolism (PE)].
4. Prevention of venous thromboembolic events (VTE) in elective total hip or knee replacement surgery (THR, TKR).

FAQ

Q1: MAY I GET ONE SAMPLE BEFORE PLACING ORDER?
Re: Yes, we’d like to provide sample for you. For those normal products, you just need to bear the freight; for those high value products, you just need to freight and a ite product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.

 

Q2: WHICH PAYMENT IS AVAIL ABLE FOR YOUR COMPANY?
Re: In order to prompt our cooperation, there are some payment methods for your choice. T/T(USD), West- erm union, Paypal, Credit card, Alipay or Alibaba trade insurance all is ok. You can choose the one which is convenient for you.
Q3: HOW AND WHEN CAN I GET MY GOODS AFTER PAYMENT?
Re: For small quantity products, they will be delivered to you by intermational courer(DHL, FedEx, TIT, EMS, etc.) or by air. Usually it will cost 2-5 days that you can get the goods after delivery. For large quantity products, shipment is better. It will cost days to weeks to come to your destination port, which depends on where the port is.
Q4: IS THERE ANY POSSIBLE TO USE MY APPOINTED LABEL OR PACKAGE?
Re: Sure. If needed, we’d like to use label or package according to your requirement.
Q5: HOW CAN YOU GUARANTEE THE GOODS YOU OFFER IS QUALIFIED?
Re: We always believe honesty and responsibility are basis of one company, so whatever products we provide for you all are high qualifed. If the goods can’t come to the quality we promise, you can ask for refund.