bupropion in hydrochloride belongs to the aminoketone class of antidepressants. It is suitable for blunt depression and depression patients who are ineffective or intolerable to other antidepressants. Long-term high-dose administration can produce beta-adrenergic receptor down-regulation
bupropion in hydrochloride has a weak inhibitory effect on the reuptake of norepinephrine, 5-HT and dopamine, but not on monoamine oxidase. The mechanism of antidepressant action of this product is not clear, it may be related to norepinephrine and/or dopaminergic effects