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melatonin powder pure Modulation of the immune system The neuroendocrine and immune systems are interconnected, and the immune system and its products can alter neuroendocrine function. Neuroendocrine signaling also affects immune function. In the past ten years, the regulatory effect of melatonin on the immune system has attracted widespread attention. Research at home and abroad has shown that it not only affects the growth and development of immune organs, but also regulates humoral and cellular immunity, as well as cytokines. For example, melatonin powder pure can modulate cellular and humoral immunity, as well as the activities of various cytokines