niacinamide health benefits Nicotinamide
(Properties and stability)
This product is dehydrated after the action of niacin and ammonia. It is a white crystalline powder; it is relatively stable in water, ethanol, glycerin and other solvents, but its tablets should be protected from light and sealed.
(In vivo process) Nicotinamide can be absorbed through the gastrointestinal tract and distributed in various tissues, organs and body fluids of the human body. The half-life is about 45 minutes. In the treatment dose, the drug is excreted in the urine together with the metabolites niacin, n-methylnicotinamide and nicotine uric acid. As the dose increases, the excretion of the original drug also increases.
(Drug effect) Nicotinamide forms nicotinamide adenine dinucleotide (coenzyme ⅰ) and nicotinamide adenine dinucleotide (coenzyme ⅱ) with ribose, phosphate, and adenine in the body, which are responsible for lipid metabolism and tissue respiration. The components required for oxidation and glycogen decomposition can affect the normal respiration and metabolism of cells and cause pellagra when the components are lacking.Niacin is a vitamin drug, collectively referred to as vitamin PP with nicotinamide. It is used for anti-pellagra and can also be used as a blood dilator