weight loss for women over 40  Orlistat powder is an obesity treatment drug that does not act on the central nervous system. It only acts on the gastrointestinal tract. Orlistat powder prevents the hydrolysis of triacylglycerols into free fatty acids and monoacylglycerides by inhibiting the lipase of the gastrointestinal tract, reduces the absorption of dietary fat (triacylglycerol) by the intestinal mucosa, and promotes the elimination of fat from the body .