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dexamethasone betamethasone glucose metabolism and anti-inflammatory effects are 15 times that of hydrocortisone prednisone, but its sodium retention is more than a hundred times that of hydrocortisone. In primary adrenal hypofunction, It can be used in replacement therapy with glucocorticoids. It is also suitable for orthostatic hypotension caused by low renin and low aldosterone syndrome and autonomic neuropathy.