Nicotinamide (nicotinamide; niacinamide), also known as nicotinamide, is the amide compound of niacin. [1] White crystalline powder; odorless or almost odorless, bitter taste; slightly hygroscopic. It is easily soluble in water or ethanol, and soluble in glycerol. Clinically, it is mainly used to prevent and treat pellagra, stomatitis, glossitis, sick sinus syndrome, and atrioventricular block.

1. Mainly used to prevent pellagra, stomatitis, glossitis, etc.
2. For the treatment of coronary heart disease, viral myocarditis, rheumatic heart disease and a small number of digitalis poisoning and other accompanying arrhythmia (mostly applied after other drugs are ineffective).
3. Mainly used in the cardiovascular system:
⑴ Prevent and treat heart block and improve sinus node function; it can improve heart rate slowing and atrioventricular block caused by verapamil.
⑵ Used for bradycardia caused by coronary heart disease, viral myocarditis, rheumatic heart disease and digitalis poisoning. [4]